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給藥·采樣·染毒

明膠膠囊,裝藥器,投藥器

時間:2016-12-01來源:本站作者:玉研儀器

詳細介紹

動物給藥膠囊,非常適合對大鼠、小鼠進行膠囊式口部給藥。

先對藥物進行膠囊灌裝,再對大鼠或小鼠進行給藥操作。


玉研儀器公司還提供國產訂制型膠囊:腸溶性、胃溶性的大小鼠灌胃膠囊,一共四種型號,敬請來電咨詢。



各種被驗藥物需要經口投藥的情況下,使用膠囊會比其他方法來的更為合適與便利:
粉末或者固體的藥物,或者無法用導管進行投藥的情況下,使用膠囊就可以輕松投藥;
對應一些有臭味或者苦味的藥劑,能夠簡單投藥,減輕動物的痛苦;
個別制劑類藥物的投藥相當便利;
為了能夠長時間持續的發揮藥效,膠囊可以輔助充分吸收;
實驗規程中必須要用膠囊進行投藥的情況下,非常適合使用;
與藥物混在飼料中進行喂食相比,用膠囊的方法更精準且無殘留;


有多種規格型號可選,歡迎來電咨詢。



Dosing Kits include capsules, funnel, stand, tamper, dosing device & instructional video


  • Ideal for materials that are insoluble, form poor suspensions, are affected by excipients or are odorous and distasteful, e.g., sustained release beadlets, paint flakes, chromic oxide marker
  • For capsule size, species, weight, and lower GI drug delivery size see table below. Capsule holders available for dip coating in enteric solutions. Capsule sinkers available for testing in disintegration test apparatus.
  • Size 9 can be used for intra-colonic delivery via rectal insertion in rats >200-250gm.
  • Save time and money by eliminating validation of suspension / solution homogeneity.
  • Eliminate excipients absorption affects.
 

Fill Materials:

Dry materials in any form
(powder, beadlets, crystals,
paint flakes), pastes, and
non-aqueous liquids.

Disintegration Time:

Within 10 minutes in stomach.

Dosing Time & Acceptance:
< 1 min. (30 - 45 minutes for 60 rats).  
> 98% successful dosing after minimal experience (3 - 4 placebo doses per rat).


on sizes 9el, 9 and 9h.
   

Animal Weight:

See below

Lower GI Drug Delivery:

See below

 
 
 Parameter Size 9el Size 9 Size 9h Size M
 Species & Weight Rats 200g+ Rats 200g 
(min 150g)
Guinea Pig 300g+
Hamsters & Rats 150g+ Mice 25g+
 Species & Weight Lower GI Delivery n/a Rat 200g+
Guinea Pig 300g+
Hamster 
& Rat 150g+ 
Guinea Pig 300g+
Mice 30g+
 Capsule Body Capacity 0.08 ml 0.025 ml 0.013ml 0.004 ml
 Fill Weight (materials with density 1g/ml) 80 mg 25 mg 13mg 4 mg
 External Diameter Maximum 2.71 mm 2.71 mm 2.71 mm 1.27 mm
 Length When Locked Maximum 23.0 mm 8.4 mm 5.1mm 8.4 mm

 Surface area locked capsule in sq mm for enteric coating.

Not Applicable 68mm2 42 mm2 31mm2
 Weight Empty (Cap & Body) Average1 17 mg 10 mg 5mg ~2 mg
 Colors Available Clear & Opaque Clear & Opaque Clear & Opaque White
For a specific net fill weight tare the weight of each capsule body individually and then fill or use a pre-weighed amount of powder for each capsule.

Tip: Order syringes for each technician to speed dosing.

裝藥器、投藥器套裝 



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